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Impact of genetic depletion or pharmacological inhibition of LSD1 on gene expression in ovarian cancer cells [RNA-Seq]

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NIAID Data Ecosystem2026-05-01 收录
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LSD1 is frequently overexpressed and correlates with poor prognosis in patients with ovarian cancer. RNA-seq, CUT&Tag-seq and ATAC-seq were performed to determine the impact of genetic depletion or pharmacological inhibition of LSD1 on gene expresion profiles in ovarian cancer cells. RNA-seq was performed in A2780 and ES2 cells treated with 1 µM LSD1 inhibitor ZY0511 or DMSO for 24 hours.

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2023-12-06
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