Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) co-crystallized with 3-Hydroxy-1-methyl-5-((3-(trifluoromethyl)phenoxy)methyl)-1H-pyrazole-4-carboxylic acid
收藏Protein Data Bank Japan2025-12-24 更新2026-03-21 收录
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Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) co-crystallized with 3-Hydroxy-1-methyl-5-((3-(trifluoromethyl)phenoxy)methyl)-1H-pyrazole-4-carboxylic acid Descriptor: 1-methyl-3-oxidanyl-5-[[3-(trifluoromethyl)phenoxy]methyl]pyrazole-4-carboxylic acid, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... Authors: Goyal, P, Sainas, S, Pippione, A.C, Boschi, D, Al-Kadaraghi, S. Deposit date: 2018-11-09 Release date: 2018-12-19 Last modified: 2025-12-24 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies. Eur J Med Chem, 163, 2018
创建时间：
2018-11-09
