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Restriction sensitivity of L10 mutants and V116D to primate TRIM5αs.

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For the complete profile of titration curves, see Supplemental Data (Figure S3). Representative results were shown from at least three independent experiments. ++; restricted more than 10-fold compared to wild type, -; restricted less than two-fold compared to wild type, and: +; partially restricted in between above two criteria. Chimeric TRIM5α of human RBCC domain fused with specified B30.2 domain nd, not done.

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2011-03-31
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