Fragile X syndrome (FXS) is caused by transcriptional silencing of the FMR1 gene during embryonic development with the consequent loss of the encoded fragile X mental retardation protein (FMRP). The p
To elucidate birth-associated gene expression changes in the V-SVZ cells, scRNA-seq of the whole V-SVZ of the lateral wall of the lateral ventricles at E18.5, full-term P2, preterm P0, and preterm P3
Cell epigenomics depends on the marks released by transcription factors operating via the assembly of complexes that induce focal changes of DNA and histone structure. Among these factors is REST, a r
Our work aims to characterize the role of Zrf1 in the generation and maintenance of neural progenitor cells (NPCs) Overall design: Gene expression profile of shCtrl and shZrf1 cells during generation
