Single cell gene expression in mouse Hematopoietic cell and Blood after Plasmodium stimulated. Single cell gene expression in mouse Hematopoietic cell and Blood after Plasmodium stimulated

Plasmodium infection induced change in the Bone marrow and Blood cells. Here we addressed whether a prior Plasmodium infection would imapct the cell type and gene expression of Bone marrow and Blood cells by single cell RNA-seq. Overall design: Mice were infected with Plasmodium yoelii for 4 weeks and subjected to CLP-induced sepsis for twenty-four hours. Bone marrow were harvest and sort by FACS for single cell RNA-seq. PBMC were harvest for single cell RNA-seq .