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Transcription profiling of human chronic lymphocytic leukemia patients expressing high or low levels of ZAP70 mRNA

ChEBI2009-04-25 更新2026-07-21 收录

白血病分子分型

ZAP70基因表达分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-12734 数据链接链接失效反馈

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资源简介：

Transcription profiling of human chronic lymphocytic leukemia patients expressing high or low levels of ZAP70 mRNA

应用场景：

创建时间：

2009-04-25

白血病分子分型

表观遗传靶点

Aberrant gene expression patterns in acute myeloid leukemia (AML) with balanced chromosomal translocations are often associated with direct or indirect dysregulation of epigenetic modifiers. Previousl

NIAID Data Ecosystem90

Gene expression profiling of CEBPA double and single mutant and CEBPA wild type AML.

白血病分子分型

CEBPA基因

Mutations in CCAAT/enhancer binding protein alpha (CEBPA) are seen in 5-14% of acute myeloid leukemia (AML) and have been associated with a favorable clinical outcome. Most AMLs with CEBPA mutations s

NIAID Data Ecosystem50

Supplementary Table S5 & 6: GSEA of SY-1425 response from Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist

白血病分子分型

RARα激动剂转录响应

GSEA of transcriptional response to SY-1425 in RARA-high cell lines in perturbation gene sets & GSEA of transcriptional response to SY-1425 in RARA-high cell lines in hallmark/pathways and perturbatio

Figshare2017-10-01 更新00

Amplified EPOR/JAK2 genes define a unique subtype of acute erythroid leukemia

白血病分子分型

白血病靶向治疗

Acute erythroid leukemia (AEL) is a unique subtype of acute myeloid leukemia characterized by prominent erythroid proliferation, whose molecular basis is poorly understood. To elucidate the underlying

NIAID Data Ecosystem50

Chromatin accessibility maps of chronic lymphocytic leukemia identify subtype-specific epigenome signatures and transcription regulatory networks. Homo sapiens

癌症表观遗传学

白血病分子分型

Chronic lymphocytic leukemia (CLL) is characterized by substantial clinical heterogeneity, despite relatively few genetic alterations. To provide a basis for studying epigenome deregulation in CLL, we

NIAID Data Ecosystem40

Transcription profiling of human chronic lymphocytic leukemia patients expressing high or low levels of ZAP70 mRNA

资源简介：

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