Supplementary Figures
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Figure S1. Funnel plot of the studies that assessed the risk of respiratory tract infections with IL-12/23 and IL-23 antagonists. Begg’s test P = 0.67; Egger’s tests P = 0.065.
Figure S2. Meta-analysis of Mantel Haenszel risk difference of respiratory tract infections (RTIs) with IL-12/23 and IL-23 antagonists to assess the differential risk of RTIs by underlying autoimmune diseases.
Figure S3. (A) Meta-analysis of Mantel Haenszel risk difference of upper respiratory tract infections with IL-12/23 and IL-23 antagonists. (B) Funnel plot of the studies that assessed the risk of upper respiratory tract infections with IL-12/23 and IL-23 antagonists. Begg’s test P = 0.81; Egger’s tests P = 0.46.
Figure S4. (A) Meta-analysis of Mantel Haenszel risk difference of viral upper respiratory tract infections with IL-12/23 and IL-23 antagonists. (B) Funnel plot of the studies that assessed the risk of viral upper respiratory tract infections with IL-12/23 and IL-23 antagonists. Begg’s test P < 0.001; Egger’s tests P = 0.019.
Figure S5. (A) Meta-analysis of Mantel Haenszel risk difference of lower respiratory tract infections with IL-12/23 and IL-23 antagonists. (B) Funnel plot of the studies that assessed the risk of lower respiratory tract infections with IL-12/23 and IL-23 antagonists. Begg’s test P < 0.001; Egger’s tests P = 0.55.
Figure S6. Funnel plot of the studies that assessed the risk of infectious pneumonia with IL-12/23 and IL-23 antagonists. Begg’s test P < 0.001; Egger’s tests P = 0.93.
Figure S7. Funnel plot of the studies that assessed the risk of non-infectious ILD with IL-12/23 and IL-23 antagonists. Begg’s test P < 0.001; Egger’s tests P = 0.69.
创建时间：
2020-08-04
