ARID1B regulates BCL11B-mediated non-canonical Activin signaling to maintain mesenchymal stem cell homeostasis in the mouse incisor.

NIAID Data Ecosystem2026-05-02 收录

干细胞稳态调控

基因信号通路机制

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237305 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2024-06-12

Retinoid X receptor promotes hematopoietic stem cell fitness and quiescence by repressing MYC pathway activation [RXR_CnR]

干细胞稳态调控

MYC信号通路表观遗传学

Hematopoietic stem cells (HSCs) maintain homeostasis and fitness by balancing self-renewal and differentiation. Alterations to the symmetry of HSC divisions reduce quiescence and induce myeloid/megaka

NIAID Data Ecosystem60

Non-catalytic functions of Tet2 are essential to regulate hematopoietic stem and progenitor cell homeostasis. Non-catalytic functions of Tet2 are essential to regulate hematopoietic stem and progenitor cell homeostasis

干细胞稳态调控

Tet2非催化功能

To identify genes that are influenced by the catalytic and non-catalytic functions of Tet2 in hematopoietic stem and progenitor cells (HSPCs), we analyzed the gene expression profiles of Tet2 catalyti

NIAID Data Ecosystem60

Integrated analysis identifies key determinants of embryonic stem cell identity and homeostasis

干细胞稳态调控

多能性分子网络

Despite RNAi-based screens to uncover genes controlling embryonic stem cell (ESC) identity, the pluripotency network remains poorly characterized, as does the precise molecular mechanisms underlying t

NIAID Data Ecosystem40

Early B Cell Factor 2 Regulates Hematopoietic Stem Cell Homeostasis in a Cell-Nonautonomous Manner

干细胞稳态调控

细胞非自主性调控

Early B Cell Factor 2 Regulates Hematopoietic Stem Cell Homeostasis in a Cell-Nonautonomous Manner

ChEBI2011-04-26 更新60

STAT1 is essential for hematopoietic stem cell function and maintains a MHC IIhi stem cell subset that resists myeloablation and neoplastic expansion. STAT1 is essential for hematopoietic stem cell function and maintains a MHC IIhi stem cell subset that resists myeloablation and neoplastic expansion

干细胞稳态调控

骨髓增殖性肿瘤病理机制

Adult hematopoietic stem cells (HSCs) are predominantly quiescent and can be activated in response to acute stress such as infection or cytotoxic insults. STAT1 is a pivotal mediator of interferon (IF

NIAID Data Ecosystem50

ARID1B regulates BCL11B-mediated non-canonical Activin signaling to maintain mesenchymal stem cell homeostasis in the mouse incisor.

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