Crystal structure of the catalytic domain of MMP-13 complexed with N-(3-methoxybenzyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-2-carboxamide
收藏Protein Data Bank Japan2023-11-08 更新2026-03-21 收录
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Crystal structure of the catalytic domain of MMP-13 complexed with N-(3-methoxybenzyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-2-carboxamide Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Collagenase 3, ... Authors: Oki, H, Tanaka, Y. Deposit date: 2014-05-12 Release date: 2014-09-24 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1′′ binding site. Bioorg.Med.Chem., 22, 2014
创建时间：
2014-05-12
