Structure of the Human Anaplastic Lymphoma Kinase in Complex with Crizotinib (PF-02341066)
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Structure of the Human Anaplastic Lymphoma Kinase in Complex with Crizotinib (PF-02341066) Descriptor: 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine, TYROSINE-PROTEIN KINASE RECEPTOR Authors: McTigue, M, Deng, Y, Liu, W, Brooun, A, Timofeevski, S, Marrone, T, Cui, J.J. Deposit date: 2010-08-24 Release date: 2010-09-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure Based Drug Design of Crizotinib (Pf-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal-Epithelial Transition Factor (C-met) Kinase and Anaplastic Lymphoma Kinase (Alk). J.Med.Chem, 54, 2011
创建时间：
2010-08-24
