Dearomatization of Pyridines: Stereoselective Synthesis of Functionalized [1,2,4]Triazolo[4,3‑a]pyridines
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The stereoselective preparation of functionalized [1,2,4]triazolo[4,3-a]pyridines from N-tosylhydrazones and pyridines was developed through the dearomatization of pyridines. The current transformation features good step- and atom-economy, high diastereoselectivity, and the efficient formation of four new carbon–heteroatom bonds in the corresponding product tetrahydro pyridines.
创建时间:
2023-12-19



