Stereoselective Total Synthesis of KAE609 via Direct Catalytic Asymmetric Alkynylation to Ketimine
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https://figshare.com/articles/dataset/Stereoselective_Total_Synthesis_of_KAE609_via_Direct_Catalytic_Asymmetric_Alkynylation_to_Ketimine/2126359
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资源简介:
A direct catalytic
asymmetric alkynylation protocol is applied
to provide the requisite enantioenriched propargylic α-tertiary
amine, allowing for the stereoselective total synthesis of KAE609
(formerly NITD609 or cipargamin).
创建时间:
2016-02-13



