Examples of expected proportion of VG that is VA in models of flux in linear metabolic pathways with a model flux J∝[Σi(1/Ei)]−1 for a system with 10 loci in which 8 are invariant wild type and two (B, C) are mutants.
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Enzyme activities are Ei = 1 for loci 3 to 8, EBB = ECC = 1, values of Ebb and Ecc are listed, and heterozygotes are intermediate, e.g. ECc = ½(1+Ecc), assuming gene frequency distributions as in Table 2. Flux modelled as [39].aUniformbU-shaped with population size of 100cU-shaped with population size of 1000
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2015-12-02



