Macaca mulatta-derived SIV-g140-specific scFv circular consensus sequences

NIAID Data Ecosystem2026-05-25 收录

抗体发现与工程

SIV/HIV免疫病理

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https://www.ncbi.nlm.nih.gov/sra/SRP125114 数据链接链接失效反馈

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资源简介：

The study aimed to characterize a phage display library generated from an SIV-infected Rhesus macaque using single molecule, real time sequencing.

创建时间：

2018-05-01

Initiation of ART during Early Acute HIV Infection Preserves Mucosal Th17 Function and Reverses HIV-Related Immune Activation

SIV/HIV免疫病理

早期抗病毒治疗干预

Mucosal Th17 cells play an important role in maintaining gut epithelium integrity and thus prevent microbial translocation. Chronic HIV infection is characterized by mucosal Th17 cell depletion, micro

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Exosomal miR - 21 causes neurotoxicity via TLR7 signaling in SIV neurological disease.. Exosomal miR - 21 causes neurotoxicity via TLR7 signaling in SIV neurological disease.

外泌体神经毒性机制

SIV/HIV免疫病理

Exosomes from the brains of rhesus macaques were isolated and characterized, both with and without simian immunodeficiency virus (SIV) induced central nervous system (CNS) disease. Small RNA sequencin

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Role of NKG2a/c + CD8 + T cells in pathogenic versus non-pathogenic SIV infections

SIV/HIV免疫病理

肠道免疫调节

Some viruses have established an equilibrium with their host. African green monkeys (AGM) display persistent high viral replication in blood and intestine during Simian immunodeficiency virus (SIV) in

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Severe genital herpes infections in HIV-infected individuals with impaired herpes simplex virus-specific CD8(+) cytotoxic T lymphocyte responses

SIV/HIV免疫病理

CD8+T细胞反应与疱疹严重度关联

The specific mechanisms underlying the varied susceptibility of HIV-infected (HIV+) individuals to opportunistic infections (OI) are still incompletely understood. One hypothesis is that quantitative

PubMed Central1997-09-16 更新40

Early Skewed Distribution of Total and HIV-Specific CD8+ T-Cell Memory Phenotypes during Primary HIV Infection Is Related to Reduced Antiviral Activity and Faster Disease Progression

SIV/HIV免疫病理

CD8+ T细胞分化

The important role of the CD8+ T-cells on HIV control is well established. However, correlates of immune protection remain elusive. Although the importance of CD8+ T-cell specificity and functionality

Figshare2016-01-15 更新20

Macaca mulatta-derived SIV-g140-specific scFv circular consensus sequences

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