Chromatin state and chromatin architecture in mouse embryonic craniofacial tissue, neural crest cell culture model and human primary craniofacial tissue

Examination of the chromatin state and chromatin architecture of a region on human chromosome 7 and the orthologous region on mouse chromosome 6. ChIP-seq for multiple histone marks, RNA-seq, HiC and 4C-seq in a cell culture model of human cranial neural crest and mouse, both wild type and CRISPR/Cas9 edited with HiC of primary human tissue for comparison of chromatin architecture. Human raw data is being submitted to dbGaP [CS17_HiC]