APE1 Mn-bound phosphorothioate substrate complex with abasic ribonucleotide DNA
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APE1 Mn-bound phosphorothioate substrate complex with abasic ribonucleotide DNA Descriptor: DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-R(P*(YA4))-D(P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA-(apurinic or apyrimidinic site) lyase, ... Authors: Freudenthal, B.D, Hoitsma, N.M. Deposit date: 2021-02-11 Release date: 2021-08-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.56 Å) Cite: Altered APE1 activity on abasic ribonucleotides is mediated by changes in the nucleoside sugar pucker. Comput Struct Biotechnol J, 19, 2021
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2021-02-11
