Age does not alter the intrinsic proliferative and differentiating potentials of myofiber MPCs.
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https://figshare.com/articles/dataset/_Increased_Stiffness_in_Aged_Skeletal_Muscle_Impairs_Muscle_Progenitor_Cell_Proliferative_Activity_/1516175
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(A) Graph showing the cumulative population doubling of primary MPCs (or myoblasts) isolated from adult (n = 3) and aged (n = 3) mice. The proliferation measurements were performed on three passages of each cell line. (B) Graph showing the fusion index of adult (n = 3) and aged (n = 3) MPC cell lines. The fusion index was determined by counting myosin heavy chain-positive cells that contained more than two nuclei. Representative images of myosin heavy chain (MF20, red) immunostaining, with nuclei in blue (DAPI), in cells used for the fusion index calculations. All data are expressed as means ± SEM.
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创建时间:
2015-08-21



