K562 lysate CHKA target engagement with CETSA

NIAID Data Ecosystem2026-05-02 收录

肿瘤药物靶点验证

CETSA技术应用

数据链接：

https://www.omicsdi.org/dataset/pride/PXD058045 数据链接链接失效反馈

官方服务：

资源简介：

Studying the target enagement of UNC0638 and UNC737 in K562 cell lysate with CETSA.

创建时间：

2025-01-28

DYRK1a inhibitor mediated rescue of Drosophila models of Alzheimer’s disease-Down Syndrome phenotypes

神经退行性疾病模型

肿瘤药物靶点验证

Alzheimer’s disease (AD) is the most common neurodegenerative disease which is becoming increasingly prevalent due to ageing populations resulting in huge social, economic, and health costs to the com

NIAID Data Ecosystem100

LPA and PA displace [3H]rosiglitazone from PPARγ-LBD.

配体-受体相互作用

肿瘤药物靶点验证

Increasing concentrations of lipids were evaluated for the ability to displace [3H]rosiglitazone from PPARγ LBD. LPA, lysophosphatidic acid; PA, phosphatidic acid. The results are expressed as the mea

Figshare2015-12-02 更新40

Thermal Shift Assay Data

蛋白质稳定性

肿瘤药物靶点验证

https://pubmed.ncbi.nlm.nih.gov/33479120/

Figshare2024-05-20 更新30

BindingDB Entry 50018569: Discovery and Optimization of Potent and Orally Available CTP Synthetase Inhibitors for Use in Treatment of Diseases Driven by Aberrant Immune Cell Proliferation.

肿瘤药物靶点验证

抑制剂筛选

Small molecule binding data for protein CTP synthase 1 and CTP synthase 2, Uniprot P17812, P70303, P70698, Q5U2N0, and Q9NRF8

DataCite Commons2024-04-26 更新90

SOURCE DATA: Nicotinamide N-methyltransferase inhibition improves limb function in experimental peripheral artery disease