To systematically characterize the kinome of the CCA, the proteomic and phosphoproteomic profiling of CCA tumors with NATs was performed using LC-MS/MS (Figure 1). After the extraction and digestion o

NIAID Data Ecosystem30

MiR-145-5p is Down-Regulated in Human Extrahepatic Cholangiocarcinoma and Regulates SRGAP2 and Rac1. MiR-145-5p is Down-Regulated in Human Extrahepatic Cholangiocarcinoma and Regulates SRGAP2 and Rac1

胆管癌分子机制

小RNA功能分析

The overall objective of this study was to explore aberrantly expressed microRNAs (miRNAs) and investigate their clinical significances in patients with extrahepatic cholangiocarcinoma (ECCA). Overall

NIAID Data Ecosystem20

miRNA profiling of biliary intraepithelial neoplasia reveals step-wise tumorigenesis in cholangiocarcinoma. miRNA profiling of biliary intraepithelial neoplasia reveals step-wise tumorigenesis in cholangiocarcinoma

胆管癌分子机制

肿瘤miRNA

Biliary intraepithelial neoplasia (BilIN) is a common precursor lesion of distal cholangiocarcinoma (dCCA). However, the sequence leading from a single epithelial layer in normal biliary epithelia to

NIAID Data Ecosystem60

Over-Expression of Nerve Growth Factor-β in Human Cholangiocarcinoma QBC939 Cells Promote Tumor Progression

胆管癌分子机制

肿瘤微环境

Aims It has been shown that nerve growth factor-β (NGF-β) promoted the initiation and progression of many tumors, and we have previously demonstrated that the expression of NGF-β was associated with t

NIAID Data Ecosystem30

Effect of YAP overexpression on HuCCT1 cholangiocarcinoma cell line transcriptome

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