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Retinoic acid directs the development and transcriptional programming of intestinal dendritic cells

ChEBI2015-08-01 更新2026-07-12 收录

免疫细胞发育

视黄酸信号调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-68399 数据链接链接失效反馈

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资源简介：

Retinoic acid directs the development and transcriptional programming of intestinal dendritic cells

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创建时间：

2015-08-01

免疫细胞发育

单细胞转录组学

The functions of innate lymphoid cells (ILCs) in immune system are increasingly appreciated, whereas the early development of ILCs in human remains elusive. In this study, we sorted humanhematopoietic

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Ly6D+ Siglec-H+ precursors contribute to conventional dendritic cells via a Zbtb46+ Ly6D+ intermediary stage

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Plasmacytoid and conventional dendritic cells (pDC and cDC) are generated from progenitor cells in the bone marrow and it was shown that commitment to pDCs or cDC subtypes may occur in earlier and lat

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TCR density in early iNKT cell precursors regulates agonist selection and subset differentiation in mice

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T细胞受体

We address the question of the nature of the signal perceived by iNKT cells promoting their specification, we analyzed iNKT cell development in relevant TCR Vα14-Jα18 alpha chain transgenic mice (Vα14

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Unraveling human T cell development using scRNA-seq

免疫细胞发育

单细胞转录组学

T cells develop in the thymus from multipotent lymphoid precursors. During this gradual differentiation process thymocytes go through several decision points, before they fully mature into conventiona

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Ontogeny and transcriptional regulation of Thetis cells [Flex]

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肠道免疫耐受

Thetis cells (TCs), a recently identified family of RORgt+ antigen-presenting cells (APCs), comprise four subsets, including the TC IV subset that instructs tolerance to gut microbiota and food antige

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Retinoic acid directs the development and transcriptional programming of intestinal dendritic cells

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