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Concise, Stereoselective Approach to the Spirooxindole Ring System of Citrinadin A

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NIAID Data Ecosystem2026-03-06 收录
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The spirooxindole ring system of citrinadin A has been synthesized with excellent control over the absolute stereochemistry at the spirocenter. The key step involves a novel diastereoselective DMDO-mediated oxidative rearrangement employing an 8-phenylmenthol chiral auxiliary on the indole nitrogen.

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2016-06-03
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