Repair-seq screens for modulators of base editor efficiency

NIAID Data Ecosystem2026-03-12 收录

碱基编辑器效率优化

功能基因组筛选

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA721212 数据链接链接失效反馈

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资源简介：

Repair-seq screens measuring the effect of gene knockdown on the sequence outcomes produced by base editors.

创建时间：

2021-04-11

Data sheet index below 1.

功能基因组筛选

肿瘤代谢

In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank a

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CRISPR/Cas9 mutagenesis screening identifies PRDM1 as a key regulator of the natural killer T cell central memory program and effector function. CRISPR/Cas9 mutagenesis screening identifies PRDM1 as a key regulator of the natural killer T cell central memory program and effector function

功能基因组筛选

NKT细胞免疫治疗

Natural killer T cells (NKTs) are a promising platform for cancer immunotherapy, but few genes involved in regulation of NKT therapeutic activity have been identified. To discover regulators of NKT fu

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Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae

细胞周期调控

功能基因组筛选

Regulation of cell cycle progression is fundamental to cell health and reproduction, and failures in this process are associated with many human diseases. Much of our knowledge of cell cycle regulator

Figshare2016-01-18 更新20

Epinephelus malabaricus Genome and Transcriptome data

鱼类基因组学

功能基因组筛选

Chromosome level genome assembly of the Malabar grouper (Epinephelus malabaricus) based on PacBio HiFi data and PhaseGenomics scaffolding. This project contains all the raw data, including: 1) PacBio

NIAID Data Ecosystem30

Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis

癌症免疫治疗

功能基因组筛选

Tumour antigen (TA)-targeting monoclonal antibody (mAb) therapies drive cancer cell elimination in large part by triggering macrophage phagocytosis. However, cancer cells evade phagocytosis by mechani

NIAID Data Ecosystem30

Repair-seq screens for modulators of base editor efficiency

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