Data from: New Crystal Forms and Amorphous Phase of Sophoricoside: X-Ray Structures and Characterization

Sophoricoside, which is an isoflavone glycoside found in many plant
species, has recently attracted attention because of its anti-fertility
activity. One solvent-free form, two solvatomorphs and an amorphous phase
of sophoricoside are reported for the first time. X-ray diffractometry,
differential scanning calorimetry, thermal gravimetric analysis and
Fourier-transform infrared spectroscopy were used to characterize the
different forms. The results show that factors such as crystal symmetry,
intermolecular arrangement, conformational flexibility, hydrogen-bonding
interactions and solvent incorporation lead to different solid-state
forms. An investigation of the transformations of the four forms showed
that they can interconvert with each other under certain conditions.
Amorphous phase and solvatomorphism were unstable but can improve the
solubility of sophoricoside in water.