Txnrd2

ENCODES a protein that exhibits protein homodimerization activity; protein-containing complex binding; thioredoxin-disulfide reductase (NADPH) activity; INVOLVED IN response to hyperoxia; response to selenium ion; response to xenobiotic stimulus; PARTICIPATES IN pyrimidine metabolic pathway; selenoamino acid metabolic pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; Reperfusion Injury; autism spectrum disorder (ortholog); FOUND IN axon; dendrite; mitochondrion; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene

编码一种表现出蛋白质同源二聚化活性的蛋白质；蛋白质复合物结合；硫氧还蛋白二硫键还原酶（NADPH）活性；参与对高氧反应；对硒离子反应；对外来物质刺激反应；参与嘧啶代谢途径；硒氨基酸代谢途径；与实验性糖尿病、再灌注损伤、自闭症谱系障碍（同源）相关；存在于轴突、树突、线粒体中；与（+）五味子素B、2,3,7,8-四氯二苯并-对-二恶英、2,4,6-三硝基甲苯相互作用。