Replication Data for: Discrete subset of monocyte-derived cells among typical conventional type 2 dendritic cells can efficiently cross present

Dendritic cells (DCs) and macrophages share close developmental pathways but also functional features and therefore, the boundary between these two cell lineages has become blurred. However, even more refined phenotypic or functional characterization and deeper understanding of DC and macrophage ontogeny, have helped to delineate pre-DC derived conventional DCs (cDCs) including cDC1s and cDC2s from monocyte-derived macrophages. Here we have further refined DC/macrophage cells and report that classically defined cDC2s contain also a discrete population of monocyte-derived cells with functional DC features, such as cross presentation.