The Prognostic Importance of Changes in Renal Function during Treatment for Acute Heart Failure Depends on Admission Renal Function

BackgroundWorsening and improving renal function during acute heart failure have been associated with adverse outcomes but few studies have considered the admission level of renal function upon which these changes are superimposed.ObjectivesThe objective of this study was to evaluate definitions that incorporate both admission renal function and change in renal function.Methods696 patients with acute heart failure with calculable eGFR were classified by admission renal function (Reduced [R, eGFR