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Structure of Aurora-2 in complex with PHA-680626

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Protein Data Bank Japan2023-12-13 更新2026-03-21 收录
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Structure of Aurora-2 in complex with PHA-680626 Descriptor: 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE, ARSENIC, SERINE THREONINE-PROTEIN KINASE 6 Authors: Cameron, A.D, Izzo, G, Storici, P, Rusconi, L, Fancelli, D, Varasi, M, Berta, D, Bindi, S, Forte, B, Severino, D, Tonani, R, Vianello, P. Deposit date: 2006-09-08 Release date: 2006-11-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: 1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile. J. Med. Chem., 49, 2006
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2006-09-08
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