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Crystal structure of HIV-1 reverse transcriptase in complex with rilpivirine (TMC278) based analogue

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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Crystal structure of HIV-1 reverse transcriptase in complex with rilpivirine (TMC278) based analogue Descriptor: (2E)-3-[4-({6-[(4-methoxyphenyl)amino]-7H-purin-2-yl}amino)-3,5-dimethylphenyl]prop-2-enenitrile, Gag-Pol polyprotein Authors: Patel, D, Bauman, J.D, Das, K, Arnold, E. Deposit date: 2012-11-22 Release date: 2013-01-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.2964 Å) Cite: A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants. Retrovirology, 9, 2012

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2012-11-22
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