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Crystal Structure of the second bromodomain of human Polybromo-1 (PB1) in complex with compound 16

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Protein Data Bank Japan2025-10-08 更新2026-04-25 收录
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Crystal Structure of the second bromodomain of human Polybromo-1 (PB1) in complex with compound 16 Descriptor: (2S)-5-chloro-2-(3-methylphenyl)-2,3-dihydroquinazolin-4(1H)-one, Protein polybromo-1, ZINC ION Authors: Nunez, R, Smith, B.C. Deposit date: 2023-01-11 Release date: 2024-01-24 Last modified: 2025-10-08 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Polybromo-1 Bromodomain Inhibitor Selectivity Is Mediated by a Unique Ligand-Binding Pocket Acs Med.Chem.Lett., 2025

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2023-01-11
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