cryo-EM structure of Staphylococcus aureus(ATCC 29213) 50S ribosome in complex with MCX-190.

cryo-EM structure of Staphylococcus aureus(ATCC 29213) 50S ribosome in complex with MCX-190. Descriptor: 23S ribosomal RNA, 5S ribosomal RNA, 7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid, ... Authors: Li, Y, Lu, G, Li, J, Pei, X, Lin, J. Deposit date: 2024-01-28 Release date: 2024-07-24 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (2.65 Å) Cite: Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024