Characteristics of individual studies included in the meta-analysis.

MI, myocardial infarction; CVD, cardiovascular disease; ACS, acute coronary syndrome; IHD, ischemic heart disease; NA, not available; MONICA, the study focus on multinational monitoring of trends and determinants in cardiovascular disease; Inter99, the study focus on effect on IHD incidence of individually tailored non-pharmacological intervention on lifestyle using a newly developed computer-based health educational tool; CGPS, Copenhagen General Population Study; CCHS, Copenhagen City Heart Study; CIHDS, Copenhagen Ischemic Heart Disease Study. aThe power calculation was performed using Quanto software http://hydra.usc.edu/gxe/.