Ras:GTP binds p120-RasGAP
收藏reactome.org2025-03-25 收录
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p120-RasGAP (RASA1) binds to activated Ras (Ras:GTP) through its GAP-related catalytic domain, which is sufficient for stimulating the Ras GTPase activity. p120-RasGAP accelerates the intrinsic GTPase activity of Ras to promote Ras inactivation (Yao et al. 1995).
p120-RasGAP（RASA1）通过其GAP相关催化域与激活的Ras（Ras:GTP）结合，此结合足以激发Ras GTP酶活性。p120-RasGAP可加速Ras的内源性GTP酶活性，进而促进Ras的失活（Yao等，1995年）。
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