five

Identification of transcriptomic signatures for differentiation of CD4+ T cell subsets

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE210222
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To investigate transciprtomic landscape changes during the Th cell activation induced by Th cell-specific cytokines, we stimulated naïve CD4+ T cells with immobilized anti-TCR mAb and anti-CD28 mAb for 48 hours under Th0, Th1, Th2, Th17, or Treg cell culture conditions. We then performed gene expression profiling analysis of RNA-seq data for naïve CD4+ T cells, Th0, Th1, Th2, Th17, and Treg cells (n=4 per group)
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2023-02-10
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