Synthesis of Pyridazine-Based α‑Helix Mimetics
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A versatile synthesis of pyridazine-based small molecule α-helix mimetics (A) is presented. Modular C–C, C–N, and C–O bond-forming reactions allow for the inclusion of a variety of aliphatic, basic, aromatic, and heteroaromatic side chain moieties. This robust synthesis is suitable for the preparation of small pyridazine-based libraries.
创建时间:
2016-10-05



