Data for: The 3-dimensional genome drives the evolution of asymmetric gene duplicates via enhancer capture-divergence
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https://datadryad.org/dataset/doi:10.5061/dryad.x69p8czv0
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资源简介:
Previous models of duplication-based new gene evolution have overlooked
the role of genome architecture. The enhancer-capture divergence model
provides a one-step mechanism for altering the expression of a
pre-existing protein. By duplicating into a region of the genome that is
under the influence of a pre-existing enhancer, distal duplication of an
existing gene provides for immediate augmentation of spatiotemporal
expression of the existing gene. In the related manuscript, we examine the
local chromosomal conformations for a newly evolved gene HP6/Umbrea, which
appears to have undergone the enhacer-capture divergence process. While
all data from the associated manuscript are publicly available through
permanent NCBI repositories, additional related 4C-Seq data was generated
but did not appear in the final manuscript. The following data set
consists of 1) raw reads from 4C-Seq experiments performed on D.
melanogaster, D. yakuba, D. erecta, and D. pseudoobscura for HP6/Umbrea
and a neighboring locus, 2) barcodes for de-multiplexing the reads, and 3)
code for running analyses from the related manuscript.
提供机构:
Dryad
创建时间:
2024-12-10



