Analysis of proteomics data (S5 Table) to identify proteins in the TNFα+2DG treatment group that were significantly more or significantly less abundant relative to TNFα treatment group.

See Materials and methods for details. Orange: subset of proteins from S5 Table significantly induced by TNFα treatment relative to vehicle, and depleted during TNFα treatment in the presence of 2DG relative to TNFα treatment alone. Blue: Gene Ontology analysis output of the 239 proteins significantly induced by TNFα treatment relative to vehicle, and depleted during TNFα treatment in the presence of 2DG relative to TNFα treatment alone. Bold ontology terms are represented in Fig 5B. Yellow = Limit of detection (LOD) data imputation values (see materials & methods) Pale yellow: proteins significantly induced by TNFα treatment relative to vehicle, and depleted during TNFα treatment in the presence of 2DG relative to TNFα. Pale green: proteins significantly induced by TNFα treatment relative to vehicle, and depleted during TNFα treatment in the presence of 2DG relative to TNFα treatment alone that are involved in response to cytokine and are known to be glycosylated (Fig 5B and 5C).
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