Xrcc4

ENCODES a protein that exhibits 3' overhang single-stranded DNA endodeoxyribonuclease activity (ortholog); DNA binding (ortholog); FHA domain binding (ortholog); INVOLVED IN cellular response to lithium ion; central nervous system development (ortholog); DN2 thymocyte differentiation (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH Chromosome Aberrations (ortholog); genetic disease (ortholog); isolated growth hormone deficiency type IA (ortholog); FOUND IN chromosome, telomeric region (ortholog); condensed chromosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; atrazine

编码一种具有3'突出单链DNA端内切核酸酶活性（同源）的蛋白质；DNA结合（同源）；FHA结构域结合（同源）；参与细胞对锂离子的反应；中枢神经系统发育（同源）；DN2胸腺细胞分化（同源）；参与非同源末端连接途径的双链断裂修复；与染色体畸变（同源）相关；遗传疾病（同源）；孤立性生长激素缺乏症类型IA（同源）；存在于染色体、端粒区域（同源）；浓缩染色体（同源）；细胞质（同源）；与2,3,7,8-四氯二苯并-对二恶英；2,6-二硝基甲苯；三嗪相互作用。