Direct comparison of the apparent affinities (<i>K</i><sub>D</sub> values, nM) determined by solution methods (MSD and KinExA) and SPR (Biacore 8K) on flat chips (average of C1 and CMD-P) and 3D-hydrogels (average of CM5 and CMD200M).
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Thirty-two mAbs are included for this comparison and are ranked by their MSD/SPR affinity correlation (best to worst). ND = not determined; NB = non-binder in the assay; Bold = kd-limited in the Biacore SPR capture-based assay. See Fig 4B.
创建时间：
2020-03-05
