Crystal Structure of EGFR-T790M/C797S in Complex with Covalent Pyrrolopyrimidine 19h
收藏Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal Structure of EGFR-T790M/C797S in Complex with Covalent Pyrrolopyrimidine 19h Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, ~{N}-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-methylpropoxy)-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide Authors: Niggenaber, J, Mueller, M.P, Rauh, D. Deposit date: 2019-07-09 Release date: 2019-10-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S. Chem Sci, 10, 2019
创建时间:
2019-07-09



