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Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor JQ1

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Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor JQ1 Descriptor: (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, 1,2-ETHANEDIOL, Bromodomain containing 2, ... Authors: Filippakopoulos, P, Picaud, S, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bradner, J.E, Structural Genomics Consortium (SGC) Deposit date: 2010-08-29 Release date: 2010-10-06 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Selective inhibition of BET bromodomains. Nature, 468, 2010
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2010-08-29
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