Structure of a membrane-bound inositol phosphorylceramide synthase and ceramide complex

Structure of a membrane-bound inositol phosphorylceramide synthase and ceramide complex Descriptor: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoate, Inositol phosphorylceramide synthase catalytic subunit AUR1, Inositol phosphorylceramide synthase regulatory subunit KEI1, ... Authors: Chen, J.H, Ke, Y, Zhang, M, Yu, H.J. Deposit date: 2025-06-19 Release date: 2026-03-11 Last modified: 2026-05-13 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Molecular insights into fungal inositol phosphorylceramide synthesis and its inhibition by antifungal aureobasidin A. Nat Commun, 17, 2026