The expression of ILT4 on peripheral blood monocytes of sepsis mice at 24 h after CLP was significantly higher (1292.00 ± 143.70 vs. 193.50 ± 52.54, P < 0.05), while the expression of MHC-II on mon
Determine genome-wide open chromatin in P14 memory CD8 T cells 30 days after septic insult Overall design: A small number of naïve P14 CD8 T cells (Thy1.1) were adoptively transferred into congenicall
Sepsis describes the life-threatening systemic inflammatory response (SIRS) of an organism to an infection and is the leading cause of mortality on intensive care units (ICU) worldwide. An acute episo
In this prospective observational cohort study, we found transcriptional evidence that persistent immune dysfunction was associated with 28-day mortality in both COVID-19 and non-COVID-19 septic patie