Sepsis is a systemic infection that enhances host vulnerability to secondary infections normally controlled by T cells. Using CLP sepsis model, we observed that sepsis induces apoptosis of circulating
Blood monocytes serve as the first line of host defense and are equipped to recognize and respond to infection by triggering an immune-inflammatory response. While most information on these cells come
The expression of ILT4 on peripheral blood monocytes of sepsis mice at 24 h after CLP was significantly higher (1292.00 ± 143.70 vs. 193.50 ± 52.54, P < 0.05), while the expression of MHC-II on mon
Sepsis predisposes the host to a number of infectious sequelae, particularly the development of nosocomial pneumonia. Mechanisms by which sepsis results in impairment of lung antibacterial host defens