Metal Cocatalyzed Tandem Alkynylative Cyclization Reaction of in Situ Formed N‑Iminoisoquinolinium Ylides with Bromoalkynes via C–H Bond Activation
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资源简介：
Silver triflate and copper(I) iodide cocatalyzed direct alkynylation and cyclization reaction of in situ formed N-iminoisoquinolinium ylides with bromoalkynes is described. The reaction proceeds efficiently through a combination of C–H activation and subsequent tandem reaction in one pot, leading to diverse H-pyrazolo[5,1-a]isoquinolines in good yields under mild reaction conditions.
创建时间：
2016-02-20
