Human serotonin 5-HT3A receptor in complex with vortioxetine (detergent, ECD only, active/distorted conformation)

Human serotonin 5-HT3A receptor in complex with vortioxetine (detergent, ECD only, active/distorted conformation) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ... Authors: Lopez-Sanchez, U, Nury, H. Deposit date: 2022-11-09 Release date: 2024-05-15 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors. Nat.Struct.Mol.Biol., 31, 2024