Histone methyltransferases SDG25/ATX1 regulate heat stress memory by antagonizing DNA remethylation

Heat stress is a great threat to plant growth because of their sessile lifestyle. Here, we show that histone methyltransferases SDG25 and ATX1 regulate gene expression and antagonize DNA remethylation under recovery stage after long-term high temperature treatment by catalyzing the methylation of histone H3K4 loci. RNA-Seq: 16 samples, wild type (WT) and sdg25-1/atx1-2 (DM) treated by long-term heat stress (R0) or living in suitable temperature (C0), WT and DM recovery from stress for 24 hours (R24) or living in suitable temperature (C24), both of which are in two biological replicates. Bisulfite-Seq: 12 samples, WT and DM recovery from long-term heat stress for 24 hours (R24) or living in suitable temperature (C24), both of which are in three biological replicates.