Lipid Brain Atlas - All main discoveries replicated with alternative clustering methods

Validation of lipizones by alternative clustering methods. Eachpage of this file reports the major figures and findings of the paper using an alternativeclustering method, as described in the Main text and Methods. The subplots include: aheatmap of the normalized and sorted confusion matrix comparing the lipizones reportedin the paper and the clusters obtained by the alternative method; a spatial plot withmatched color coding for representative sections along the rostrocaudal axis; a heatmap ofthe normalized and sorted confusion matrix comparing the lipizones and the anatomicaldivisions; a spatial plot of the 4 major brain divisions found by lipidomic clustering; aheatmap of the normalized and sorted confusion matrix comparing the lipizones and celltypes; spatial plots for four lipizones matching cell type territories; zoom-in spatial plotsshowing cortical lipizones; the histogram with red bar replicating Figure 3j; a stackedbarplot and a scatterplot replicating Figure 5e; spatial views on the cerebellar lipizones;half-brain spatial plots showing example white matter lipizones; a violin plot and anaccompanying barplot replicating Figure 4b; density plots for the mediolateral distributionof white matter lipizones, replicating Figure 4l; spatial zoom-ins of the axon bundlelipizones and their differential lipids, replicating Figure 4k.