Crystal structure of human PRMT3 in complex with an allosteric inhibitor (PRMT3- KTD)
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Crystal structure of human PRMT3 in complex with an allosteric inhibitor (PRMT3- KTD) Descriptor: 1-(1,2,3-benzothiadiazol-6-yl)-3-(2-oxo-2-phenylethyl)urea, PRMT3 protein, UNKNOWN ATOM OR ION Authors: Dobrovetsky, E, Dong, A, Liu, F, Li, F, Tempel, W, Siarheyeva, A, Hajian, T, Smil, D, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Schapira, M, Jin, J, Vedadi, M, Structural Genomics Consortium (SGC) Deposit date: 2012-10-30 Release date: 2012-12-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors. J. Med. Chem., 56, 2013
创建时间：
2012-10-30
