The cell surface glycoprotein CD137, which is also known as 4-1BB, belongs to the group of co-stimulatory immune receptors and is a member of the TNF receptor superfamily (TNFRSF). It is preferentiall

NIAID Data Ecosystem80

Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization

肠道微生物免疫轴

白细胞功能调控

The intestinal microbiota influences the development and function of myeloid lineages such as neutrophils, but the underlying molecular mechanisms are unresolved. Using gnotobiotic zebrafish, we ident

NIAID Data Ecosystem80

CaMK2D is a critical regulator of coactivation of leukemia stem cell factors in acute myeloid leukemia.. CaMK2D is a critical regulator of coactivation of leukemia stem cell factors in acute myeloid leukemia.

白细胞功能调控

AML（急性髓系白血病）

Relapse is one of the biggest challenges in treating acute myeloid leukemia (AML) due to leukemia stem cells (LSCs) resisting chemotherapy, providing a cellular reservoir to form the basis for relapse

NIAID Data Ecosystem80

CD97 is a Critical Regulator of Acute Myeloid Leukemia Stem Cell Function

白细胞功能调控

AML靶向治疗

Despite significant efforts to improve therapies for acute myeloid leukemia (AML), clinical outcomes remain poor. Understanding the mechanisms that regulate the development and maintenance of leukemic

NIAID Data Ecosystem80

Evaluation of effect of PTEN gene deletion in mouse CD4+ Th1 clones after stimulation

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