RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell functionality

Mendeley Data2026-04-09 收录

糖尿病遗传机制

细胞功能分析

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Raw PCR gel electrophoresis and Western blots for the study "RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell functionality"

Additional file 2: of Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimerâs disease-related proteins

神经退行性疾病蛋白质

细胞功能分析

Table S2. GO Elite analysis of all 4,133 proteins identified in mouse microglia by TMT mass spectrometry. (XLSX 63 kb)

NIAID Data Ecosystem80

Polymer-coated gold nanoparticles target Age-Associated B cells in vivo

纳米免疫靶向

细胞功能分析

Engineered gold nanoparticles (GNPs) have become a useful tool in various therapeutic and diagnostic applications. Uncertainty remains regarding possible impacts of GNPs to the immune system. In this

NIAID Data Ecosystem70

HIV exposed seronegative (HESN) compared to HIV infected individuals have higher frequencies of telomeric Killer Immunoglobulin-like Receptor (KIR) B motifs; Contribution of KIR B motif encoded genes to NK cell responsiveness

HIV免疫机制

细胞功能分析

Previously, we showed that Killer Immunoglobulin-like Receptor (KIR)3DS1 homozygotes (hmz) are more frequent in HIV exposed seronegative (HESN) than in recently HIV infected (HIV+) individuals. KIR3DS

Figshare2017-09-23 更新50

Point mutations in the PDX1 transactivation domain impair human β-cell development and function (mRNA microarray). Point mutations in the PDX1 transactivation domain impair human β-cell development and function (mRNA microarray)

干细胞β细胞功能

糖尿病遗传机制

Missense mutations in coding region of PDX1 predispose to type-2 diabetes mellitus as well as cause MODY through largely unexplored mechanisms. Here, we screened a large cohort of subjects with increa

NIAID Data Ecosystem80

GWAS data on human pancreatic islets from 191 donors - Lund

糖尿病遗传机制

胰岛特异性eQTL分析

Most signals detected by genome-wide association studies map to non-coding sequence and their tissue-specific effects influence transcriptional regulation. However, many key tissues and cell-types req

NIAID Data Ecosystem70

RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell functionality

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