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Transcriptome profiles of Streptomyces coelicolor A3(2) wild type treated with kanamycin and iron

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NIAID Data Ecosystem2026-03-13 收录
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We determine genes that responsible for iron induced resistance to kanamycin in Streptomyces coelicolor. Iron acts as a inducing agent for resistance to bactericidal antibiotics with concentration dependent manner. Identification of iron-dependent differentially expressed genes in wild-type by RNA-seq identified more than 100 genes. This series encompasses the RNA-seq data of our study. Overall design: Transcriptome profiles from combination of kanamycin/iron-treated or non-treated wild-type were obtained using Illumina NovaSeq. RNA samples were prepared in biologically independent duplicates.

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2022-05-06
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